Next Generation Sequencing (NGS) Lab Build-Outs
Advanced Infrastructure for High-Throughput Genetic Sequencing
Precision Lab Builds designs Next Generation Sequencing (NGS) laboratory build-outs for organizations implementing high-throughput genetic sequencing programs. NGS labs support large-scale DNA and RNA sequencing used in clinical genomics, oncology, rare disease analysis and research applications.
NGS laboratories require specialized infrastructure that supports complex instrumentation, data-intensive workflows and strict contamination control across multiple processing stages.
What Is an NGS Laboratory?
An NGS lab is a specialized molecular laboratory designed to sequence millions of DNA or RNA fragments simultaneously. These labs enable comprehensive genetic analysis far beyond targeted molecular testing, supporting broad panels, exomes, genomes and transcriptomic workflows.
NGS labs are often built as advanced extensions of molecular genetics laboratories, with additional requirements for automation, bioinformatics and data security.
Core Sequencing Workflows Supported
Precision Lab Builds supports NGS lab infrastructure for a wide range of sequencing applications, including:
Targeted Gene Panels
Focused sequencing for specific diseases or clinical indications
Whole Exome Sequencing (WES)
Analysis of protein-coding regions of the genome
Whole Genome Sequencing (WGS)
Comprehensive genome-wide sequencing
RNA Sequencing (RNA-seq)
Gene expression and transcriptome analysis
Oncology & Somatic Variant Sequencing
Tumor profiling and mutation detection
NGS Lab Design Considerations
NGS labs require precise workflow segmentation and advanced infrastructure planning, including:
Separate pre-PCR, library preparation, sequencing and post-sequencing areas
Automation-compatible bench layouts
Environmental controls for sensitive reagents
Robust electrical, cooling, and ventilation systems
Secure data storage and bioinformatics workspaces
Our designs emphasize throughput, accuracy, and scalability, enabling organizations to expand test menus and sequencing capacity without reworking core infrastructure.
How NGS Labs Fit Within Genetic Testing Programs
Molecular Genetics Labs support targeted gene-level testing
Cytogenetics & CMA Labs analyze chromosomal abnormalities
NGS Labs enable deep, comprehensive genomic analysis
Many organizations integrate NGS labs with existing molecular and cytogenetic operations, but NGS workflows require dedicated planning due to data volume, automation and regulatory complexity.
Who This Is For
NGS lab build-outs are commonly implemented by:
Hospital and health system laboratories
Reference and specialty genomics labs
Academic and translational research centers
Precision medicine and oncology programs
Compliance & Operational Alignment
All NGS lab builds are designed to support:
CLIA certification requirements
CAP accreditation standards
State laboratory regulations
Validation, quality control, and data governance workflows
Precision Lab Builds provides laboratory infrastructure and operational design support only and does not perform diagnostic testing or patient-facing services.
Related Genetic Lab Build-Outs
Plan an NGS Laboratory
If your organization is preparing to implement or expand next generation sequencing capabilities, Precision Lab Builds can help design an NGS laboratory aligned with your sequencing goals, compliance requirements and long-term growth strategy.
Call: 940-594-3775 or Email: info@corepathservices.com